Getting pregnant isn’t the whole story
Conceive with your healthiest sperm
Built by Harvard physicians and fertility experts
Reversible sperm damage raises pregnancy risk
Every guy’s sperm is constantly under assault from dietary, lifestyle and environmental factors. This leads to avoidable complications across pregnancy, birth and early childhood.
Miscarriage
Early pregnancy loss is associated with higher DNA fragmentation index
Fetal Growth Issues
Preterm delivery, low birth weight and ICU needs are associated with male factors
Time to Conception
Lower sperm quality makes it more difficult for couples to get pregnant
Morning Sickness
Male habits before conception lead to higher rates of hyperemesis gravidarum
Phthalates
Ultra-processed food
Alcohol
Smoking & vaping
Vitamin deficiencies
Environmental toxins
Obesity
What is DNA fragmentation?
Drivers of sperm DNA damage are all around us, but traditional parameters like sperm count, motility and morphology tell us nothing about genetic quality.
Chromatin stores DNA
DNA is carried in a compressed form called chromatin, located in the head of the sperm
DNA gets damaged
Nutrition shortfalls, harmful habits and toxic exposures cause breaks in the chromatin structure
Fertilization still occurs
Some sperm damage prevents conception, but DNA damage is still passed on to offspring
The Optimal Protocol
Targeted interventions have been shown in clinical studies to dramatically improve DNA fragmentation, motility, morphology, and count — reducing complications during pregnancy, at birth and into childhood
Targeted Supplements
All-natural, backed by science and delivered to your door
Lifestyle Modifications
Improve on the habits that kick sperm when they’re down
Exposure Reduction
Avoid common chemicals and pollutants that damage sperm
Our proprietary formulation contains the highest-quality non-prescription ingredients, manufactured at pharmaceutical-grade facilities
Designed by fertility experts and based directly on clinical studies
All-natural ingredients
Get tuned up in 6 months flat
Two 3-month sperm cycles is all it takes to do your part for the health of your future family
Risk assessment
As a first step, take our two-minute assessment to better understand your most critical sperm damage contributors
Make positive changes
Optimal is with you every step of the way, recommending small steps toward healthier habits and practical ways to avoid toxic exposures in everyday life
We’ll help you track your progress and up the ante as you meet your goals
Conceive with confidence
One sperm maturation cycle takes about 3 months, but change doesn’t happen overnight. Running the Optimal Protocol for two sperm cycles earns you the right to say you held up your end of the genetic bargain
Get started free
Take our two-minute assessment to better understand your most critical sperm damage contributors.